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\/>\n\u540c\u3058\u7cd6\u8cea\u3067\u3082\u3001\u7c73\u98ef\u3084\u30d1\u30f3\u306e\u3088\u3046\u306a\u56fa\u5f62\u7269\u306a\u3089\u3001\u3093\u3067\u3001\u80c3\u3067\u6d88\u5316\u3057\u3066\u2026\u2026\u3068\u3044\u3046\u6642\u9593\u304c\u304b\u304b\u308b\u305f\u3081\u3001\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3082\u6bd4\u8f03\u7684\u7de9\u3084\u304b\u3067\u3059\u3002\u3068\u3053\u308d\u304c\u3001\u6db2\u4f53\u3060\u3068\u6d88\u5316\u306e\u624b\u9593\u304c\u3044\u3089\u306a\u3044\u305f\u3081\u3001\u3059\u3050\u306b\u30c9\u30ab\u30f3\u3068\u8840\u7cd6\u5024\u3092\u4e0a\u3052\u3066\u3057\u307e\u3044\u307e\u3059\u3002<br \/>\n\u3053\u306e\u6025\u6fc0\u306a\u8840\u7cd6\u5024\u4e0a\u6607\u73fe\u8c61\u3092\u3001\u5c02\u9580\u7684\u306b\u306f\u300c\u8840\u7cd6\u5024\u30b9\u30d1\u30a4\u30af\u300d\u3068\u8868\u73fe\u3057\u307e\u3059\u3002<br \/>\n\u8840\u7cd6\u5024\u30b9\u30d1\u30a4\u30af\u304c\u8d77\u304d\u308b\u3068\u3001\u4e0a\u304c\u308a\u3059\u304e\u305f\u8840\u7cd6\u5024\u3092\u4e0b\u3052\u308b\u305f\u3081\u306b\u3001\u81b5\u81d3\u304b\u3089\u305f\u304f\u3055\u3093\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u5206\u6ccc\u3055\u308c\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u305d\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u4f5c\u7528\u3067\u3001\u4eca\u5ea6\u306f\u8840\u7cd6\u5024\u304c\u4e0b\u304c\u308a\u3059\u304e\u3001\u75b2\u52b4\u611f\u3084\u5410\u304d\u6c17\u306a\u3069\u306e\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3059\u308f\u3051\u3067\u3059\u3002<br \/>\n\u8840\u7cd6\u5024\u30b9\u30d1\u30a4\u30af\u3092\u983b\u7e41\u306b\u8d77\u3053\u3057\u3066\u3044\u308b\u3068\u3001\u305d\u306e\u305f\u3073\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u5927\u91cf\u306b\u5206\u6ccc\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u3001\u6b21\u7b2c\u306b\u81b5\u81d3\u304c\u75b2\u5f0a\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u3084\u304c\u3066\u3001\u75b2\u308c\u304d\u3063\u305f\u81b5\u81d3\u306e\u50cd\u304d\u304c\u60aa\u304f\u306a\u3063\u3066\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u51fa\u3059\u30bf\u30a4\u30df\u30f3\u30b0\u304c\u9045\u308c\u307e\u3059\u3002\u3059\u308b\u3068\u3001\u8840\u7cd6\u5024\u3092\u4e0b\u3052\u308b\u3053\u3068\u304c\u96e3\u3057\u304f\u306a\u308a\u3001\u7cd6\u5c3f\u75c5\u3092\u767a\u75c7\u3057\u307e\u3059\u3002<br \/>\n\u3064\u307e\u308a\u3001\u6db2\u4f53\u306e\u7cd6\u8cea\u306f\u3001\u6162\u6027\u75b2\u52b4\u306e\u539f\u56e0\u306b\u306a\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u7cd6\u5c3f\u75c5\u306b\u7f79\u308a\u3084\u3059\u3044\u5371\u967a\u306a\u98df\u6750\u306a\u306e\u3067\u3059\u3002\u7cd6\u5c3f\u75c5\u306b\u7f79\u308c\u3070\u3001\u305d\u306e\u5408\u4f75\u75c7\u3067\u814e\u81d3\u304c\u3084\u3089\u308c\u3001\u3055\u3089\u306b\u75b2\u308c\u3084\u3059\u3044\u4f53\u306b\u306a\u308b\u3053\u3068\u306f\u672c\u66f8\u306e2\u7ae0\u3067\u8aac\u660e\u3057\u305f\u901a\u308a\u3067\u3059\u3002<br \/>\n\u6c17\u3092\u3064\u3051\u3066\u307b\u3057\u3044\u306e\u306f\u3001\u5065\u5eb7\u306b\u826f\u3055\u305d\u3046\u306a\u91ce\u83dc\u30b8\u30e5\u30fc\u30b9\u3084\u30b9\u30dd\u30fc\u30c4\u30c9\u30ea\u30f3\u30af\u306b\u3082\u7cd6\u8cea\u304c\u305f\u304f\u3055\u3093\u542b\u307e\u308c\u3066\u3044\u308b\u3053\u3068\u3067\u3059\u3002<br \/>\n\u5b9f\u969b\u306b\u3001\u5b66\u6821\u306e\u90e8\u6d3b\u52d5\u3067\u30b9\u30dd\u30fc\u30c4\u30c9\u30ea\u30f3\u30af\u3092\u591a\u98f2\u3057\u3066\u3044\u305f\u4e2d\u5b66\u751f\u304c\u3001\u3044\u304d\u306a\u308a\u9ad8\u8840\u7cd6\u3067\u660f\u5012(\u3053\u3093\u3068\u3046)\u3057\u3001\u6551\u6025\u8eca\u3067\u642c\u9001\u3055\u308c\u305f\u4e8b\u4f8b\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3053\u3046\u3057\u305f\u30b1\u30fc\u30b9\u3092\u300c\u30da\u30c3\u30c8\u30dc\u30c8\u30eb\u75c7\u5019\u7fa4\u300d\u3068\u547c\u3073\u307e\u3059\u304c\u3001\u82e5\u304f\u3057\u3066\u91cd\u75c7\u306e\u7cd6\u5c3f\u75c5\u3092\u767a\u75c7\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u3001\u5b9f\u306b\u6df1\u523b\u306a\u554f\u984c\u3067\u3059\u3002<br \/>\n\u305f\u3068\u3048\u3070\u3001\u30b3\u30ab\u30fb\u30b3\u30fc\u30e9\u306f\u30da\u30c3\u30c8\u30dc\u30c8\u30eb500mL\u306e\u5834\u5408\u300156.5\u30b0\u30e9\u30e0\u306e\u7cd6\u8cea\u3092\u542b\u3093\u3067\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u89d2\u7802\u7cd614\u500b\u5206\u306b\u76f8\u5f53\u3057\u307e\u3059\u3002<br \/>\n\u3068\u304f\u306b\u70ad\u9178\u304c\u5165\u3063\u3066\u3044\u308b\u98f2\u307f\u7269\u306f\u3001\u6e05\u6dbc\u611f\u306b\u3054\u307e\u304b\u3055\u308c\u7518\u3055\u306b\u6c17\u3065\u304d\u306b\u304f\u304f\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305f\u3081\u3057\u306b\u84cb\u3092\u958b\u3051\u305f\u307e\u307e\u653e\u7f6e\u3057\u3001\u70ad\u9178\u304c\u629c\u3051\u305f\u72b6\u614b\u3067\u98f2\u3093\u3067\u307f\u308b\u3068\u3001\u7802\u7cd6\u6c34\u306e\u3088\u3046\u306a\u7518\u3055\u306b\u9a5a\u304f\u306f\u305a\u3067\u3059\u3002<br \/>\n\u3064\u307e\u308a\u3001\u6e05\u6dbc\u98f2\u6599\u6c34\u306f\u3001\u81ea\u5206\u304c\u60f3\u50cf\u3057\u3066\u3044\u308b\u3088\u308a\u3082\u9059(\u306f\u308b)\u304b\u306b\u591a\u304f\u306e\u7802\u7cd6\u3092\u6442\u3063\u3066\u3057\u307e\u3046\u98f2\u307f\u7269\u306a\u306e\u3067\u3059\u3002<br \/>\n\u7f36\u30b3\u30fc\u30d2\u30fc\u3082\u3001\u307b\u3069\u3088\u3044\u82e6\u307f\u304c\u3042\u308b\u304c\u3086\u3048\u306b\u3001\u7518\u3059\u304e\u308b\u3053\u3068\u304c\u308f\u304b\u3089\u306a\u304f\u306a\u308a\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u3082\u306e\u3092\u65e5\u5e38\u7684\u306b\u53e3\u306b\u3057\u3066\u3044\u308b\u3068\u3001\u7c21\u5358\u306b\u7cd6\u8cea\u4e2d\u6bd2\u306b\u9665\u308a\u307e\u3059\u3002<br \/>\n\u4ed5\u4e8b\u3092\u9014\u4e2d\u3067\u629c\u3051\u51fa\u3057\u3001\u9650\u3089\u308c\u305f\u55ab\u7159\u6240\u3067\u4e00\u5fc3\u4e0d\u4e71\u306b\u30bf\u30d0\u30b3\u3092\u5438\u3063\u3066\u3044\u308b\u4eba\u305f\u3061\u306f\u3001\u30cb\u30b3\u30c1\u30f3\u4e2d\u6bd2\uff08\u4f9d\u5b58\u75c7\uff09\u306b\u9665\u3063\u3066\u3044\u307e\u3059\u3002\u540c\u69d8\u306b\u3001\u3042\u308b\u30bf\u30a4\u30df\u30f3\u30b0\u3067\u7f36\u30b3\u30fc\u30d2\u30fc\u306a\u3069\u3092\u98f2\u3080\u306e\u304c\u6c7a\u307e\u308a\u306b\u306a\u3063\u3066\u3044\u308b\u4eba\u3082\u307e\u305f\u3001\u7cd6\u8cea\u4e2d\u6bd2\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u306e\u3067\u3059\u3002<br \/>\n\u307e\u305a\u306f\u3001\u6db2\u4f53\u306e\u7cd6\u8cea\u3092\u300c\u53b3\u7981\u300d\u3068\u3057\u3001\u30da\u30c3\u30c8\u30dc\u30c8\u30eb\u306e\u98f2\u6599\u3067\u3082\u3001\u30df\u30cd\u30e9\u30eb\u30a6\u30a9\u30fc\u30bf\u30fc\u3084\u7cd6\u8cea\u306e\u5165\u3063\u3066\u3044\u306a\u3044\u304a\u8336\u985e\u3092\u9078\u3076\u7656\u3092\u3064\u3051\u3066\u304f\u3060\u3055\u3044\u3002<br \/>\n\u306a\u304a\u3001\u6e05\u6dbc\u98f2\u6599\u6c34\u306e\u30b7\u30e5\u30ef\u30b7\u30e5\u30ef\u3057\u305f\u523a\u6fc0\u304c\u597d\u304d\u306a\u4eba\u306f\u3001\u30cf\u30a4\u30dc\u30fc\u30eb\u306a\u3069\u3092\u3064\u304f\u308b\u3068\u304d\u306b\u4f7f\u3046\u300c\u70ad\u9178\u6c34\u300d\u3092\u98f2\u3093\u3067\u3082\u3044\u3044\u3067\u3057\u3087\u3046\u3002\u306a\u3093\u306e\u5473\u4ed8\u3051\u3082\u3057\u3066\u3044\u306a\u3044\u70ad\u9178\u6c34\u306a\u3089\u3001\u4f59\u8a08\u306a\u7cd6\u8cea\u3092\u6442\u3063\u3066\u3057\u307e\u3046\u61f8\u5ff5\u306f\u3042\u308a\u307e\u305b\u3093\u3002<br \/>\n\u6c34\u306f\u98f2\u3081\u3070\u98f2\u3080\u307b\u3069\u814e\u81d3\u306b\u826f\u3044\u3068\u3044\u3046\u3053\u3068\u304c\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3067\u304d\u308c\u3070\u4e00\u65e52\u30ea\u30c3\u30c8\u30eb\u4ee5\u4e0a\u306e\u6c34\u5206\u3092\u6442\u308b\u3088\u3046\u306b\u5fc3\u639b\u3051\u307e\u3057\u3087\u3046\u3002<br \/>\n&#8212;&#8212;&#8212;-\u7267\u7530 \u5584\u4e8c\uff08\u307e\u304d\u305f\u30fb\u305c\u3093\u3058\uff09AGE\u7267\u7530\u30af\u30ea\u30cb\u30c3\u30af\u9662\u95771979\u5e74\u3001\u5317\u6d77\u9053\u5927\u5b66\u533b\u5b66\u90e8\u5352\u696d\u3002\u5730\u57df\u533b\u7642\u306b\u5f93\u4e8b\u3057\u305f\u5f8c\u3001\u30cb\u30e5\u30fc\u30e8\u30fc\u30af\u306e\u30ed\u30c3\u30af\u30d5\u30a7\u30e9\u30fc\u5927\u5b66\u533b\u751f\u5316\u5b66\u8b1b\u5ea7\u306a\u3069\u3067\u3001\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u306e\u539f\u56e0\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308bAGE\u306e\u7814\u7a76\u3092\u7d045\u5e74\u9593\u884c\u3046\u3002\u3053\u306e\u9593\u3001\u8840\u4e2dAGE\u306e\u6e2c\u5b9a\u6cd5\u3092\u4e16\u754c\u3067\u521d\u3081\u3066\u958b\u767a\u3057\u3001\u300cThe New England Journal of Medicine\u300d\u300cScience\u300d\u300cTHE 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