\u79c1\u305f\u3061\u306e\u8001\u5f8c\u304c\u5909\u308f\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u2026\u3002\u305d\u3093\u306a\u6700\u65b0\u7814\u7a76\u304c\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002\u6771\u4eac\u5927\u5b66\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u3089\u304c\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306a\u3069\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u3055\u308c\u308b\u300c\u8001\u5316\u7d30\u80de\u300d\u3092\u53d6\u308a\u9664\u304f\u3053\u3068\u306b\u3001\u5b9f\u9a13\u3067\u6210\u529f\u3057\u307e\u3057\u305f\u3002\u5e74\u3092\u3068\u308b\u3053\u3068\u3067\u8d77\u304d\u308b\u75c5\u6c17\u306e\u6539\u5584\u3084\u4e88\u9632\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u3001\u753b\u671f\u7684\u306a\u7814\u7a76\u3067\u3059\u3002\u3081\u3056\u307e\u30578\u306f\u3001\u5b9f\u969b\u306b\u7814\u7a76\u3092\u884c\u3063\u305f\u6559\u6388\u306b\u8a71\u3092\u805e\u304d\u307e\u3057\u305f\u3002
\n\u4e16\u754c\u306e\u533b\u7642\u95a2\u4fc2\u8005\u304c\u671f\u5f85\u3092\u5bc4\u305b\u308b\u3001\u6700\u65b0\u306e\u8001\u5316\u306b\u95a2\u3059\u308b\u7814\u7a76\u3002\u6771\u4eac\u5927\u5b66\u533b\u79d1\u5b66\u7814\u7a76\u6240\u306e\u4e2d\u897f\u771f\u6559\u6388\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u304c\u300111\u67082\u65e5\u3001\u30a4\u30ae\u30ea\u30b9\u306e\u79d1\u5b66\u8a8c\u300c\u30cd\u30a4\u30c1\u30e3\u30fc\u300d\u306b\u300e\u8001\u5316\u3092\u201c\u9632\u3050\u201d\u7814\u7a76\u300f\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002\u4e2d\u897f\u6559\u6388\u3089\u306f\u3001\u5e74\u8001\u3044\u305f\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u5b9f\u9a13\u3067\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u306b\u3088\u308a\u300c\u8001\u5316\u7d30\u80de\u300d\u3092\u53d6\u308a\u9664\u304f\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002\u7814\u7a76\u3067\u306f\u3001\u81ea\u5df1\u306e\u514d\u75ab\u304c\u6d3b\u6027\u5316\u3055\u308c\u3066\u8001\u5316\u7d30\u80de\u304c\u6e1b\u308a\u3001\u8001\u5316\u306b\u4f34\u3046\u75c7\u72b6\u306e\u6539\u5584\u3082\u78ba\u8a8d\u3067\u304d\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002
\n\u4eca\u56de\u9664\u53bb\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u305f\u300c\u8001\u5316\u7d30\u80de\u300d\u3068\u306f\u305d\u3082\u305d\u3082\u3001\u304c\u3093\u3084\u7cd6\u5c3f\u75c5\u306a\u3069\u3001\u69d8\u3005\u306a\u75c5\u6c17\u3092\u5f15\u304d\u8d77\u3053\u3059\u4e00\u56e0\u3068\u306a\u308b\u7d30\u80de\u3067\u3059\u3002\u81d3\u5668\u5185\u306e\u7d30\u80de\u304c\u5206\u88c2\u3092\u3057\u306a\u304f\u306a\u308b\u3068\u3001\u3053\u306e\u8001\u5316\u7d30\u80de\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u52a0\u9f62\u306b\u3088\u308a\u5897\u52a0\u30fb\u84c4\u7a4d\u3057\u3066\u3044\u304d\u3001\u708e\u75c7\u306b\u3064\u306a\u304c\u308b\u7269\u8cea\u3092\u51fa\u3057\u7d9a\u3051\u3001\u3053\u308c\u304c\u75c5\u6c17\u306e\u4e00\u56e0\u306b\u306a\u3063\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002
\n\u79c1\u305f\u3061\u304c\u8003\u3048\u308b\u201c\u8001\u5316\u201d\u3068\u306f\u3001\u3053\u306e\u8001\u5316\u7d30\u80de\u306b\u3088\u308b\u3082\u306e\u306a\u306e\u3067\u3057\u3087\u3046\u304b\u3002
\n\u6771\u4eac\u5927\u5b66\u533b\u79d1\u5b66\u7814\u7a76\u6240\u30fb\u4e2d\u897f\u771f \u6559\u6388\uff1a\u3044\u308d\u3044\u308d\u306a\u539f\u56e0\u304c\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u305d\u306e\u3046\u3061\u306e1\u3064\u304c\u3001\u4f53\u4e2d\u3067\u708e\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3088\u3046\u306a\u3001\u8001\u5316\u7d30\u80de\u306e\u84c4\u7a4d\u3068\u3044\u3046\u306e\u304c\u91cd\u8981\u3060\u308d\u3046\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u3066\u3001\u305d\u308c\u3092\u6a19\u7684\u306b\u3057\u3066\u306a\u3093\u3068\u304b\u6539\u5584\u3067\u304d\u306a\u3044\u304b\u3068\u3044\u3046\u7814\u7a76\u304c\u4e16\u754c\u4e2d\u3067\u9032\u3093\u3067\u3044\u307e\u3059
\n\u8001\u5316\u7d30\u80de\u306e\u9664\u53bb\u306f\u3001\u79c1\u305f\u3061\u306e\u4eca\u5f8c\u306e\u751f\u6d3b\u306b\u3069\u306e\u3088\u3046\u306a\u5909\u5316\u3092\u3082\u305f\u3089\u3059\u306e\u3067\u3057\u3087\u3046\u304b\u3002
\n\u4e2d\u897f\u6559\u6388\u306b\u3088\u308b\u3068\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306a\u3069\u306e\u4e88\u9632\u30fb\u6539\u5584\u306b\u3064\u306a\u304c\u308a\u3001\u5065\u5eb7\u306a\u671f\u9593\u304c\u4f38\u3073\u308b\u3002\u305d\u308c\u306b\u3088\u308a\u3001\u3053\u308c\u307e\u3067\u3042\u3063\u305f\u201c\u5e73\u5747\u5bff\u547d\u3068\u5065\u5eb7\u5bff\u547d\u306e\u5dee\u201d\u304c\u9650\u308a\u306a\u304f\u30bc\u30ed\u306b\u306a\u308b\u3053\u3068\u3067\u3001\u9ad8\u9f62\u8005\u304c\u9577\u304f\u50cd\u304f\u3053\u3068\u306e\u3067\u304d\u308b\u793e\u4f1a\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3044\u307e\u3059\u3002
\n\u3053\u306e\u7814\u7a76\u3067\u3069\u3093\u306a\u3053\u3068\u306b\u671f\u5f85\u3092\u3057\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002
\n\u6771\u4eac\u5927\u5b66\u533b\u79d1\u5b66\u7814\u7a76\u6240\u30fb\u4e2d\u897f\u771f \u6559\u6388\uff1a\u4eba\u306f\u6700\u5f8c\u306e10\u5e74\u9593\u8fd1\u304f\u306f\u3001\u4f55\u3089\u304b\u306e\u5f62\u3067\u533b\u7642\u3084\u4ecb\u8b77\u3092\u5fc5\u8981\u3068\u3059\u308b\u308f\u3051\u3067\u3059\u3002\u9650\u308a\u306a\u304f\u5065\u5eb7\u306a\u6642\u9593\u3092\u4f38\u3070\u3059\u3053\u3068\u3067\u793e\u4f1a\u3001\u3042\u308b\u3044\u306f\u500b\u3005\u305d\u306e\u3082\u306e\u304c\u5e78\u305b\u306b\u66ae\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u3044\u3046\u3075\u3046\u306b\u8003\u3048\u3066\u3001\u305d\u3046\u3044\u3046\u793e\u4f1a\u306e\u5b9f\u73fe\u3092\u76ee\u6307\u3057\u3066\u3044\u304d\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059
\n\u305d\u3057\u3066\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u65b0\u305f\u306b\u69d8\u3005\u306a\u767a\u898b\u304c\u3042\u308a\u307e\u3057\u305f\u3002
\n\u307e\u305a\u4e00\u3064\u306f\u3001\u8001\u5316\u7d30\u80de\u306f\u514d\u75ab\u6a5f\u80fd\u306e\u653b\u6483\u306b\u3088\u308a\u53d6\u308a\u9664\u304b\u308c\u307e\u3059\u304c\u3001\u4e00\u90e8\u53d6\u308a\u9664\u304b\u308c\u306a\u3044\u8001\u5316\u7d30\u80de\u3082\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u84c4\u7a4d\u3059\u308b\u8001\u5316\u7d30\u80de\u306b\u306f\u3001\u514d\u75ab\u6a5f\u80fd\u304c\u50cd\u3044\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002
\n\u305d\u306e\u4e0a\u3067\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001\u30de\u30a6\u30b9\u306e\u8001\u5316\u7d30\u80de\u3068\u30d2\u30c8\u306e\u7d30\u80de\u304b\u3089\u4eba\u5de5\u7684\u306b\u4f5c\u3063\u305f\u8001\u5316\u7d30\u80de\u3092\u4f7f\u3063\u3066\u3001\u514d\u75ab\u7d30\u80de\u304b\u3089\u306e\u653b\u6483\u3092\u907f\u3051\u308b\u7269\u8cea\u306e\u6709\u7121\u3092\u7814\u7a76\u3057\u307e\u3057\u305f\u3002
\n\u305d\u306e\u7d50\u679c\u3001\u514d\u75ab\u6a5f\u80fd\u3092\u59a8\u3052\u308b\u300cPD-L1\u300d\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3001\u8001\u5316\u7d30\u80de\u306e1\u5272\u5f31\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u65b0\u305f\u306b\u308f\u304b\u3063\u305f\u306e\u3067\u3059\u3002\u3053\u306ePD-L1\u306f\u514d\u75ab\u7d30\u80de\u3067\u3042\u308b\u300cPD-1\u300d\u3068\u7d50\u3073\u3064\u304f\u3053\u3068\u306b\u3088\u3063\u3066\u514d\u75ab\u306e\u50cd\u304d\u306b\u30d6\u30ec\u30fc\u30ad\u3092\u304b\u3051\u3066\u3001\u8001\u5316\u7d30\u80de\u304c\u9664\u53bb\u3055\u308c\u306b\u304f\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002
\n\u3053\u308c\u307e\u3067\u306b\u3082\u3001\u304c\u3093\u306e\u7d30\u80de\u306e\u4e2d\u306bPD-L1\u304c\u3042\u308b\u3053\u3068\u306f\u308f\u304b\u3063\u3066\u3044\u3066\u3001PD-L1\u3068\u514d\u75ab\u7d30\u80dePD-1\u306e\u7d50\u3073\u3064\u304d\u3092\u9632\u3050\u305f\u3081\u306b\u3001\u304c\u3093\u306e\u6cbb\u7642\u3067\u306f\u300c\u30aa\u30d7\u30b8\u30fc\u30dc\u300d\u3068\u3044\u3046\u6cbb\u7642\u85ac\u304c\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u4eca\u56de\u306e\u7814\u7a76\u3067\u3001\u30aa\u30d7\u30b8\u30fc\u30dc\u3068\u540c\u69d8\u306e\u6297PD-1\u6297\u4f53\u3092\u30de\u30a6\u30b9\u306b\u4f7f\u3063\u305f\u3068\u3053\u308d\u3001\u80ba\u30fb\u809d\u81d3\u30fb\u814e\u81d3\u306e\u8001\u5316\u7d30\u80de\u304c3\u5206\u306e1\u306b\u306a\u308a\u3001\u3055\u3089\u306b\u7b4b\u529b\u306e\u56de\u5fa9\u30fb\u809d\u6a5f\u80fd\u306e\u6539\u5584\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002
\n\u307e\u3060\u30de\u30a6\u30b9\u3067\u306e\u7814\u7a76\u6bb5\u968e\u3067\u3059\u304c\u3001\u4eba\u9593\u3067\u3082\u540c\u3058\u3088\u3046\u306a\u52b9\u679c\u306f\u671f\u5f85\u3067\u304d\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002
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